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Tocris Bioscience™ ERK5-IN-1

Potent and selective ERK5 inhibitor

Brand:  Tocris Bioscience™ 5393/50

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Product Code. 18732988

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Description

Description

ERK5-IN-1 is a potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

>98%
638.8
50 mg
ERK5-IN-1
ERK5-IN-1
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