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Epredia™ Lab Vision™ NFκB/p65 (Rel A) Ab-1 Rabbit Polyclonal Antibody with BSA and azide
Epredia™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.
Marke: Epredia™ RB-1638-P
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Beschreibung
NFκ B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodimer is present in the cytoplasm in inactive form bound to its inhibitor, IdeltaB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFκB which goes to the nucleus inducing gene expression. NFκB was originally identified as transcriptional activator for kappa light chain gene in B cells.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drosophila, Xenopus. Others not known.
Epitope: C-terminal
Immunogen: A synthetic peptide from the C-terminus of human NFκB protein
Molecular Weight: 65kDa
Positive Control: Jurkat cells
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Note:
USA: RUO; Int'l: RUO
Spezifikation
| NFkappaB/p65 (Rel A) Ab-1 | |
| Polyclonal | |
| 1mg/mL | |
| Rabbit | |
| 1 mL | |
| Transcription Regulation | |
| Bovine, Canine, Drosophila, Hamster, Human, Mouse, Pig, Rabbit, Rat, Xenopus species | |
| IgG |
| Western Blot | |
| Polyclonal | |
| Unconjugated | |
| A synthetic peptide from the C-terminus of human NFkappaB protein | |
| RUO | |
| Primary | |
| Concentrated |
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