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Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein
Recombinant Protein
Marke: Invitrogen™ PV3788
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Beschreibung
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length
MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Spezifikation
| Q16584 | |
| Kinase Assay | |
| 4296 | |
| Human MAP3K11 (MLK3), GST Tag | |
| 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase | |
| MLK Kinase Family | |
| Human | |
| GST-tag | |
| -80°C, Avoid Freeze/Thaw Cycles | |
| Ser⁄Thr Kinases: TKL Group | |
| LanthaScreen™ Antibody, LanthaScreen™ Substrate, Omnia™ Bulk Substrate | |
| mitogen-activated protein kinase kinase kinase 11 | |
| Kinases & Inhibitors | |
| Liquid | |
| Immunology, Oncology, Signal Transduction |
| See Label | |
| 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 | |
| 120.1 kDa | |
| 10 μg | |
| MLK3 | |
| Unconjugated | |
| Recombinant | |
| Full length | |
| Biochemical terbium phospho-specific activity, Biochemical binding/kinetic | |
| Dry Ice | |
| MAP3K11 | |
| Insect cells | |
| Recombinant, Full Length | |
| Serine/Threonine Kinases |
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