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SS18 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA563745
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Beschreibung
Immunogen sequence: NGQMPGPNHM PMQGPGPNQL NMTNSSMNMP SSSHGSMGGY NHSVPSSQSM P Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.
Spezifikation
| SS18 | |
| Polyclonal | |
| Unconjugated | |
| SS18 | |
| D130059H17; MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; Ssxt; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; synovial sarcoma-associated Ss18-alpha; SYT | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 6760 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q15532 | |
| SS18 | |
| Recombinant protein corresponding to Human SS18 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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