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TNIP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 € - 410.00 €
Spezifikation
Antigen | TNIP2 |
---|---|
Konzentration | 0.2 mg/mL |
Anwendungen | Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin) |
Klassifikation | Polyclonal |
Konjugat | Unconjugated |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
16874644
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Proteintech
15459-1-AP-20UL |
20 μL |
145.00 €
20 Mikroliter |
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16864644
|
Proteintech
15459-1-AP-150UL |
150 μL |
410.00 €
150 Mikroliter |
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Beschreibung
TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kappa-B-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist.Spezifikation
TNIP2 | |
Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin) | |
Unconjugated | |
Rabbit | |
Rat, Mouse, Human | |
Q8NFZ5, Q99JG7 | |
231130, 305451, 79155 | |
TNIP2 Fusion Protein Ag7731 | |
Primary | |
-20°C | |
TNIP2 |
0.2 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
ABIN 2, ABIN2, FLIP1, KLIP, TNFAIP3 interacting protein 2, TNIP2 | |
TNIP2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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