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UGT8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 17982-1-AP-20UL
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Beschreibung
This antibody specifically recognizes the endogenous UGT8.
UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.Spezifikation
| UGT8 | |
| Polyclonal | |
| Unconjugated | |
| UGT8 | |
| ceramide galactosyltransferase, Cerebroside synthase, CGT, UDP glycosyltransferase 8, UGT4, UGT8 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 22239, 50555, 7368 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q09426, Q16880, Q64676 | |
| Ugt8 | |
| UGT8 Fusion Protein Ag12393 | |
| 20 μL | |
| Primary | |
| Rat, Human, Mouse | |
| Antibody | |
| IgG |
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